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Barium sulphate, a chemical compound with the formula BaSO₄, is widely recognized for its numerous applications in various industries, particularly in the field of medicine, paints, plastics, and as a component in drilling fluids. One of the distinguishing features of barium sulphate is its striking physical property its color. Understanding the color of barium sulphate not only helps in identifying the compound during handling but also plays a significant role in its applications and quality assessment.


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Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

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